Thyroid Surgery (Thyroidectomy) Indications: 

Thyroid surgery is a common operation, but one which needs to be taken seriously because of the potential complications which may occur.  Commonly, this surgery is done because of suspected cancer.  Patient risk factors, appearance on ultrasound examination or needle biopsy results may cause your surgeon to recommend surgical removal of the thyroid.   If there is a vocal cord paralysis or rapid growth of a solid mass also indicates a cancer.  Unfortunately, one of the forms of thyroid cancer, follicular carcinoma, can appear benign on needle biopsy and may also be read as benign on frozen section during surgery.   See Evaluation of Thyroid Nodule Page

From 1973 to 2002 the incidence of thyroid cancer has increase 2.4 times to 8.7 cases per 100,000 per year.  The increase was entirely due to an increase in papillary carcinoma.  The mortality from thyroid cancer has stayed unchanged at 0.5 patients per 100,000 per year.  View Article (JAMA 2006)

If the thyroid becomes so large that it compresses the trachea or esophagus surgical removal is indicated.  A thyroid cyst that recurs after a single or repeated needle drainage is also an indication for removal.  Rarely, a thyroiditis will cause scaring in the neck which also compresses the airway.  The thyroid must also be removed in this case.  However, cases of thyroiditis have an increased complication rate due to bleeding and scaring.
 

 
Thyroid Surgery (Thyroidectomy) Technique: 
 

Thyroid Surgery (Thyroidectomy) Care After Surgery: 

Depending upon the working environment, patients can expect to be off of work for one to three weeks.  Stitches are removed in five to seven days.  If removed at five days, steri-strips are usually applied to the incision.   After 24 hours the incision can be gently washed.  Antibiotic ointment should be applied to the wound twice a day.  The wound must be kept clean.

Depending upon the diagnosis, thyroid medication may be given.   If only a single thyroid lobe is removed for benign disease, and the opposite lobe is normal, then thyroid replacement is often not started.  If thyroiditis is present, then thyroid replacement should be started. 

If a total thyroidectomy is performed, thyroid replacement is mandatory.  If the thyroid was removed because of cancer, then thyroid suppressive dosages should be considered.  In cases of thyroid nodules, goiter and thyroiditis, mild thyroid suppression is controversial because of the possible risk of osteoporosis.  If the patient is placed on thyroid suppression, a bone scan for osteoporosis and supplemental calcium and vitamin D should be prescribed.  

If I-131 therapy is planned after a total thyroidectomy, Cytomel (liothyronine sodium), should be considered to shorten the time of hypothyroidism before the treatment.   Cytomel contains synthetic T3, a thyroid hormone with a short half life.  Thus, the patient is taken off of it for a shorter time before I-131 therapy, than if the patient was prescribed a T4 replacement. 

In all patients who receive thyroid replacement or suppression, TSH and Free-T4 should be routinely monitored.  If hypoparathyroidism is suspected, calcium levels will also need to be measured. 

Thyroid Surgery (Thyroidectomy) Complications:

1) Paralysis of the Recurrent Laryngeal Nerve (RLN) is the most common complication after thyroid surgery.  It can occur in approximately 2% of patients.  If one lobe of the thyroid is removed only one RLN will be placed at risk.  Injury can result in a weak, breathy voice.  However, in some patients compensation will occur and a strong raspy voice results.  In cases of a weak voice, augmentation of the vocal cords may improve the voice.

If a total thyroidectomy is performed, both RLNs are at risk.  If both RLNs are injured, the patient will have a poor airway and may require a tracheotomy.  There is no satisfactory treatment for this complication and the patient must decide between a strong voice and a good airway, both are not possible.

The picture to the right shows the appearance of the operative field after the thyroid gland is removed.  Note the left recurrent laryngeal nerve.  This nerve runs next to the undersurface of the thyroid and between the trachea and esophagus. The recurrent laryngeal nerve controls the movement of the left true vocal cord.  This nerve can be damaged during surgery, which will result in a weak, breathy voice.  



Mouse Over Picture to identify nerve. 
Click on picture to enlarge.

Chindo and Chheda reported (Archives of Otolaryngology May 2007) that the incidence of vocal cord paralysis is between 2.09% in monitored patients to 2.96% in unmonitored patients.  There was not a statistical difference between the two groups. 

2) Hypoparathyroidism:   There are four small glands next to the thyroid which control calcium metabolism.  These location of these glands are variable and they can mimic lymph nodes and globs of fat.  Two of these glands are located on each side.  If a total thyroidectomy is performed (both the right and left thyroid lobes are removed) these glands may be inadvertently removed.  If all four are removed the patient's calcium will drop over a matter of hours and cramps, tetany and cardiac arrest will develop.  Treatment is to give intravenous calcium.  After stabilization, the patient is discharged home on oral Vitamin D and calcium.   It must be stressed that these glands are hard to identify and one or two are often removed during surgery.   Repeated frozen section may be required to identify the glands.   If they can be identified after removal, they can be implanted into the local muscles where they will grow and calcium metabolism will return to normal after their function returns. 

3) Bleeding:  Because of the vascularity, bleeding can occur after the operation which can cause airway obstruction.  If this occurs, the surgical wound must be opened immediately to relieve the pressure on the trachea.