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2
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- Normal larynx in a 44 yr old non-smoker
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4
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5
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6
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8
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- Almost all cancers of the larynx are associated with smoking.
--53 of 56 larynx cancers in my practice
- Incidence increases with a 20 pk/yr history
- Quitting smoking does not decrease the patient's risk of getting a
cancer but it does prevent the risk increasing
- Smoking causes permanent genetic damage to the epithelium.
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9
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10
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- Tobacco use remains the leading preventable cause of death in the United
States, causing more than 400,000 deaths each year and resulting in an
annual cost of more than $50 billion in direct medical costs.
- Each year, smoking kills more people than AIDS, alcohol, drug abuse, car
crashes, murders, suicides, and fires---combined!
- Approximately 80% of adult smokers started smoking before the age of 18.
Every day, nearly 3,000 young people under the age of 18 become regular
smokers.
- Smokers pay twice as much for life insurance and will die an average of
over 12 years sooner than non-smokers. Smokers have more than one
chance in 10 of developing lung cancer.
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11
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- Cancer of the Esophagus & Larynx
- Asthma
- Chronic Sinusitis in children
- Symptoms
-- Dry Cough
-- Food Sticking in Lower Neck
-- Throat Pain Radiating to the Ear
-- May or May Not Have Heartburn
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12
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- Elevate head of bed by 6 to 8 inches. (Place blocks under bed posts.)
- Do not eat 4 hours before sleeping.
- Take Pepcid, Tagament or Zantac at bedtime--both are over the counter
anti-reflux medications.
- Avoid the following Foods: Fried/Fatty, Caffeine (Coffee, Tea,
Chocolate), Spices (Peppermint, spearmint, garlic, onions, cinnamon,
herbs), Alcohol, Acidic Foods, Citric Foods, Tomato Juice.
- Avoid tight clothing.
- Avoid smoking.
- If overweight, lose weight.
- Check with your doctor about contraindicated medications, aspirin etc.
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- "I am just as deaf as I am
blind. The problems of deafness are deeper and more complex, if
not more important, than those of blindness. Deafness is a much
worse misfortune. For it means the loss of the most vital stimulus-the
sound of the voice that brings language, sets thoughts astir and keeps
us in the intellectual company of man."
Helen Keller in Scotland A Personal Record Written By
Herself. Methuen & Co. Ltd. 36 Essex Street W.C.
London Page 68.
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- Family history of hearing loss.
- Congenital infections such as toxoplasmosis, syphilis, rubella, cmv, and
herpes.
- Head & face abnormalities.
- Birth weight less than 1500 grams or 3.3 lbs.
- Hyperbilirubinemia at a level to need exchange transfusion.
- Bacterial meningitis (brain infection).
- Ototoxic medications such as aminoglycosides (strong antibiotic).
- Severe depression of Apgar scores.
- Mechanical ventilation or intubation to aid in breathing.
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15
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- 3-6 months Child should respond to your voice or
speech. Does he react to your voice when he cannot see you?
- 7-10 months Should react when he hears, but cannot see, the
dog barking, telephone ringing, footsteps, someone's voice, refrigerator
opening, microwave ringing, etc.
- 11-15 months Can he point to or find familiar objects or people, when he
is asked to? Does he respond to different sounds
differently? Does he enjoy listening to music and other sounds and
try to imitate them.
- Most children by 12 months of age are starting to say single words.
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16
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17
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- The most common preventable cause to hearing loss is noise exposure.
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18
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- Source--dBA SPL
- Heavy Traffic 80 dB
- Automobile (at 20 meters) 70 dB
- Vacuum Cleaner 65 dB
- Conversational Speech (at 1 meter) 60 dB
- Quiet Business Office 50 dB
- Residential Area at Night 40 dB
- Whisper, Rustle of Leaves 20 dB
- Rustle of Leaves 10 dB
- Threshold of Audibility 0 dB
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- Source--Dangerous Level dBA SPL
- Produces Pain
140-150 dB
- Jet Aircraft During Takeoff (at 20 meters)130 dB
- Discomfort Level 120 dB
Snowmobile
Tractor Without Cab
- Rock Concert 110 dB
- 100-105 dB
Die Forging
Hammer
Gas Weed Trimmer
Chain Saw
Pneumatic Drill
- Home Lawn Mowers 95 to 100 dB
- Semi-trailers (at 20 meters) 90 dB
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20
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- Two Types Objective and Subjective
- Objective:
-- Carotid Bruit
-- Systolic Ejection Murmur
-- Venus Hum Rule Out High Intracranial Pressure
- -- Glomus Tumor MRI Best Study
- Subjective:
-- Peripheral Hearing Loss
-- If Unilateral May be Central
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21
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22
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- 50% comes from the ear
- Almost always has an Abnormal Eardrum
- 50% does not come from the ear
- Temporal Mandibular Joint Disorder
- Maxillary Sinusitis
- Reflux Disease
- Oral Pharyngeal Inflammation or Carcinoma
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23
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- This is an acute bacterial
infection usually caused by pseudomonas. The outer ear canal is
swollen shut, and the auricle is very painful to touch. Treatment
is to open the ear canal, place a wick, and treat with ear drops.
The wick is cloth or foam rubber which will allow the ear drops to
penetrate the swollen canal. Unfortunately, most oral antibiotics
are ineffective. The fluoroquinolones have some effect, but they
are not approved in children.
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24
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25
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26
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- Middle Ear Negative Pressure
- Retraction of the Ear Drum
- Ear Fluid and/or Infection
- Retraction Pocket Formation
- Cholesteatoma
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28
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- Treatment-- Antibiotics 50% Culture Positive
- Ear Tube Placement
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33
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34
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35
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- Blowing a balloon with the nose held shut.
- Blowing the nose with the nose held shut.
- Mathis bulb.
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- Perforation of eardrum
- Eardrum heals over tube
- Otitis media 33% are
pseudomonas
- Tube intrudes completely into the
middle ear
- Cholesteatoma
- Monolayer not clinical
significant
- Bleeding usually minor from a
tube granuloma
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40
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- 33% are Culture Positive for Pseudomonas
- Must Use Ear Drops
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- Almost all are Culture Positive for Pseudomonas
- Must Use Ear Drops
- Usually resolve in 1 to 2 weeks of treatment with an antibiotic and
steroid ear drop
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- Treatment initially with antibiotics
- --Amoxicillin
- --Amoxicillin/Clavulanate
- --Cefdinir.
- --Clindamycin
- Bacterial Resistance is a big problem
- --Antibiotics with a long
half life which are present for days in subtherapeutic levels foster
bacterial resistance.
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43
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44
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45
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- Types of Bacteria
- Streptococcus Pneumonia,
- Haemophilus Influenzae (this is
not the flu virus),
- Moraxella catarrhalis.
- Less commonly, Mycoplasma Pneumoniae, Streptococcus Pyogenes,
Staphylococcus Aureus along with other bacteria and viruses.
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46
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47
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- A single plasmid can carry the genes for resistance to both the
penicillin and macrolide antibiotics.
- The mechanism of penicillin resistance in this organism is by producing
a penicillin binding protein and not by producing penicillinase (an
enzyme which breaks down penicillin).
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48
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49
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50
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- No Risk Factors
- Amoxicillin 40 90 mg/kg/day
- If penicillin allergic TMP SMX
or Erythromycin-Sulfisoxazole or Macrolides
- If Treated Within Prior Month
- Amoxicillin, Sulfa or Macrolides are
NOT RECOMMENDED
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51
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- Most Likely to be Strep Pneumonia:
- Increase otalgia and fever
- Spontaneous perforation
- Risk Factors for Strep Pneumonia Resistance:
- Daycare
- Younger than 2 years of age
- Contact with an individual treated with antibiotics
- History of recurrent acute otitis media
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52
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- Mechanism of antibiotic resistance is a penicillin binding protein and
NOT by producing penicillinase.
Thus, penicillinase inhibitors will NOT be effective
- A single plasmid can carry the genes for resistance to both the penicillin
and macrolide antibiotics.
- Recommendations to increase the Ampicillin dosage to 90 mg/kg/day
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53
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- Risk Factors for Haemophilus influenzae Resistance
- Preceding therapy with amoxicillin.
- Most Likely to be Haemophilus influenzae
- Otitis-conjunctivitis Syndrome
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54
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- Mechanism of resistance is through the production of penicillinase.
- Treatment is with a penicillinase inhibitor, cefuroxime, or cefdinir.
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55
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- First Line
- Amoxicillin
- TMP-SMX
- Second Line
- Cefdinir
- Cefuroxime axetil
- Amoxicillin-clavulante
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56
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- 30% to 60% of S pneumoniae and
H influenzae strains resistant or not eradicated.
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57
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- Recommended for Children Under the Age of 2. Over the age of 2, sometimes a single
dose is recommended.
- Decrease the incidence of ear tubes by 20% but a prevention NOT a
treatment. Thus, if has recurrent
otitis media on the basis of eustachian tube dysfunction, tubes will
still be needed.
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58
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59
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- Severe Condition Can Cause Death
- Usually Caused by Streptococcal Pneumonia
- In this Patient the Strep. Pneumonia was penicillin, trimethoprim/sulfamethoxazole,
erythromycin and intermediate susceptible to Ceftriaxone
- Treated with IV Vancomycin.
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60
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61
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62
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63
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64
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- Slowly Progressive Unilateral Hearing Loss.
- Less Than 3% Present With Vertigo.
- Usually Treated With Surgery.
- 10% of the population on autopsy have this condition
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65
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- Vision
- Proprioception (sensation of position)
- Inner Ear
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66
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- A loss of control or staggering like being drunk, but the room
orientation is normal. The patient just cannot control his body.
- A lightheadedness or fainting.
- A sensation of motion or spinning.
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- Length of Spells
- Less than 10 min - Positional Vertigo
- 20 min to 24 hrs.- Menieres Disease
( tinnitus, hearing loss, vertigo & ear pressure)
- 24 hrs to one week - Viral Labyrinitis
- Over one week - Central Disease
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68
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- Characteristics of Peripheral Vertigo
- -- Latency - 5 to 6 seconds
- -- Duration - Less than 60 Seconds
- -- Adapts - Less on Repeated
Stimulation
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69
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70
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71
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72
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73
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74
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75
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- Always think Carcinoma
- Inverting papilloma
- Fungal Ball (Allergic Fungal Sinusitis)
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77
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78
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79
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80
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81
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82
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83
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84
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- 2 hours of Category I CME Credits can be obtained by studying this
course and by passing an on-line CME test.
- To take and submit the test, go to:
http://www.cmeusa.org/medicine_test_ms.htm
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